Cargando…

Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture

The inner ear contains sensory epithelia that detect head movements, gravity and sound. It is unclear how to derive these sensory epithelia from pluripotent stem cells, a process which will be critical for modeling inner ear disorders or developing cell-based therapies for profound hearing loss and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koehler, Karl R., Mikosz, Andrew M., Molosh, Andrei I., Patel, Dharmeshkumar, Hashino, Eri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739998/ https://www.ncbi.nlm.nih.gov/pubmed/23842490 http://dx.doi.org/10.1038/nature12298

Ejemplares similares

Generation of inner ear organoids with functional hair cells from human pluripotent stem cells
por: Koehler, Karl R., et al.
Publicado: (2017)

Progress in Modeling and Targeting Inner Ear Disorders with Pluripotent Stem Cells
por: Tang, Pei-Ciao, et al.
Publicado: (2020)

Unconventional Myosins in Inner-Ear Sensory Epithelia
por: Hasson, Tama, et al.
Publicado: (1997)

BMP4 signaling is involved in the generation of inner ear sensory epithelia
por: Li, Huawei, et al.
Publicado: (2005)

The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex
por: Patel, Dharmeshkumar, et al.
Publicado: (2018)

Modulation of Wnt Signaling Enhances Inner Ear Organoid Development in 3D Culture
por: DeJonge, Rachel E., et al.
Publicado: (2016)

Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia
por: Hawkins, R. David, et al.
Publicado: (2007)

Gross and Fine Dissection of Inner Ear Sensory Epithelia in Adult Zebrafish (Danio rerio)
por: Liang, Jin, et al.
Publicado: (2009)

Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells
por: Liu, Xiao-Ping, et al.
Publicado: (2016)

Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids
por: Tang, Pei-Ciao, et al.
Publicado: (2019)

Deafness-in-a-dish: modeling hereditary deafness with inner ear organoids
por: Romano, Daniel R., et al.
Publicado: (2021)

Tlx3 Promotes Glutamatergic Neuronal Subtype Specification through Direct Interactions with the Chromatin Modifier CBP
por: Shimomura, Atsushi, et al.
Publicado: (2015)

Sensory epithelia of the fish inner ear in 3D: studied with high-resolution contrast enhanced microCT
por: Schulz-Mirbach, Tanja, et al.
Publicado: (2013)

CHD7 regulates otic lineage specification and hair cell differentiation in human inner ear organoids
por: Nie, Jing, et al.
Publicado: (2022)

Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells
por: Koehler, Karl R, et al.
Publicado: (2011)

Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells
por: Jeong, Minjin, et al.
Publicado: (2018)

Apoptosis in inner ear sensory hair cells
por: Morrill, Seth, et al.
Publicado: (2017)

Defining developmental trajectories of prosensory cells in human inner ear organoids at single-cell resolution
por: Ueda, Yoshitomo, et al.
Publicado: (2023)

Regeneration of inner ear sensory epithelium using stem cells: state of art
por: Fetoni, A R, et al.
Publicado: (2010)

Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice
por: Takeda, Hiroki, et al.
Publicado: (2018)

Single cell analysis of the inner ear sensory organs
por: YIZHAR-BARNEA, OFER, et al.
Publicado: (2017)

Inner Ear
por: Arnold, Andreas, et al.
Publicado: (2010)

Actin filaments in sensory hairs of inner ear receptor cells
Publicado: (1977)

Generation of inner ear sensory neurons using blastocyst complementation in a Neurog1(+/−)−deficient mouse
por: Steevens, Aleta R., et al.
Publicado: (2021)

THE ULTRASTRUCTURE OF THE KINOCILIUM OF THE SENSORY CELLS IN THE INNER EAR AND LATERAL LINE ORGANS
por: Flock, Åke, et al.
Publicado: (1965)

Spatiotemporal dynamics of inner ear sensory and non-sensory cells revealed by single-cell transcriptomics
por: Jan, Taha A., et al.
Publicado: (2021)

Modelling inner ear development and disease using pluripotent stem cells – a pathway to new therapeutic strategies
por: Connolly, Keeva, et al.
Publicado: (2022)

Photo-click hydrogels for 3D in situ differentiation of pancreatic progenitors from induced pluripotent stem cells
por: Arkenberg, Matthew R., et al.
Publicado: (2023)

Photo-click hydrogels for 3D in situ differentiation of pancreatic progenitors from induced pluripotent stem cells
por: Arkenberg, Matthew R., et al.
Publicado: (2023)

Inner Ear Therapeutics: An Overview of Middle Ear Delivery
por: Patel, Jaimin, et al.
Publicado: (2019)

Organotypic Culture of Neonatal Murine Inner Ear Explants
por: Ogier, Jacqueline M., et al.
Publicado: (2019)

Building inner ears: recent advances and future challenges for in vitro organoid systems
por: van der Valk, Wouter H., et al.
Publicado: (2020)

HCN Channels Are Not Required for Mechanotransduction in Sensory Hair Cells of the Mouse Inner Ear
por: Horwitz, Geoffrey C., et al.
Publicado: (2010)

Scalable generation of sensory neurons from human pluripotent stem cells
por: Deng, Tao, et al.
Publicado: (2023)

Next-generation sequencing of small RNAs from inner ear sensory epithelium identifies microRNAs and defines regulatory pathways
por: Rudnicki, Anya, et al.
Publicado: (2014)

The Notch Ligand JAG1 Is Required for Sensory Progenitor Development in the Mammalian Inner Ear
por: Kiernan, Amy E, et al.
Publicado: (2006)

The Candidate Splicing Factor Sfswap Regulates Growth and Patterning of Inner Ear Sensory Organs
por: Moayedi, Yalda, et al.
Publicado: (2014)

Proteomics and the Inner Ear
por: Thalmann, Isolde
Publicado: (2001)

Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus Slices
por: Hyakumura, Tomoko, et al.
Publicado: (2019)

Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system
por: Xu, Junjun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lj11skhdolfu0aqh8ds049iied