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Rapid quantitative pharmacodynamic imaging by a novel method: theory, simulation testing and proof of principle
Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines pharmacokinetic-pharmacodynamic modeling, repeated small doses of a challeng...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740141/ https://www.ncbi.nlm.nih.gov/pubmed/23940831 http://dx.doi.org/10.7717/peerj.117 |