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Thyroid hormone treated astrocytes induce maturation of cerebral cortical neurons through modulation of proteoglycan levels

Proper brain neuronal circuitry formation and synapse development is dependent on specific cues, either genetic or epigenetic, provided by the surrounding neural environment. Within these signals, thyroid hormones (T3 and T4) play crucial role in several steps of brain morphogenesis including prolif...

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Detalles Bibliográficos
Autores principales: Dezonne, Rômulo S., Stipursky, Joice, Araujo, Ana P. B., Nones, Jader, Pavão, Mauro S. G., Porcionatto, Marimélia, Gomes, Flávia C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740295/
https://www.ncbi.nlm.nih.gov/pubmed/23964200
http://dx.doi.org/10.3389/fncel.2013.00125