The Pak4 protein kinase is required for oncogenic transformation of MDA-MB-231 breast cancer cells

The Pak4 protein kinase, normally expressed at low level in the mammary gland, is commonly overexpressed in breast cancer. Overexpression of Pak4 transforms mouse mammary epithelial cells in vitro and renders these cells tumorigenic in athymic mice in vivo. Here we show that Pak4 is also required fo...

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Detalles Bibliográficos
Autores principales: Wong, L E, Chen, N, Karantza, V, Minden, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740299/
https://www.ncbi.nlm.nih.gov/pubmed/23732710
http://dx.doi.org/10.1038/oncsis.2013.13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740299/
https://www.ncbi.nlm.nih.gov/pubmed/23732710
http://dx.doi.org/10.1038/oncsis.2013.13

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