MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes

MUC1 (CD227), a membrane tethered mucin glycoprotein, is overexpressed in >60% of human pancreatic cancers (PCs), and is associated with poor prognosis, enhanced metastasis and chemoresistance. The objective of this study was to delineate the mechanism by which MUC1 induces drug resistance in hum...

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Detalles Bibliográficos
Autores principales: Nath, S, Daneshvar, K, Roy, L D, Grover, P, Kidiyoor, A, Mosley, L, Sahraei, M, Mukherjee, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740301/
https://www.ncbi.nlm.nih.gov/pubmed/23774063
http://dx.doi.org/10.1038/oncsis.2013.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740301/
https://www.ncbi.nlm.nih.gov/pubmed/23774063
http://dx.doi.org/10.1038/oncsis.2013.16

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