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Tumor-associated soluble uPAR-directed endothelial cell motility and tumor angiogenesis

The expression of urokinase-type plasminogen activator (uPA) receptor (uPAR) correlates with the malignant phenotype of various cancers. The soluble form of uPAR (s-uPAR) is present in the circulation of cancer patients, but the role of s-uPAR in endothelial cell migration is poorly understood. Ther...

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Detalles Bibliográficos
Autores principales: Rao, J S, Gujrati, M, Chetty, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740303/
https://www.ncbi.nlm.nih.gov/pubmed/23797476
http://dx.doi.org/10.1038/oncsis.2013.19