Minimal residual disease quantification using consensus primers and high-throughput IGH sequencing predicts post-transplant relapse in chronic lymphocytic leukemia

Quantification of minimal residual disease (MRD) following allogeneic hematopoietic cell transplantation (allo-HCT) predicts post-transplant relapse in patients with chronic lymphocytic leukemia (CLL). We utilized an MRD-quantification method that amplifies immunoglobulin heavy chain (IGH) loci usin...

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Detalles Bibliográficos
Autores principales: Logan, A C, Zhang, B, Narasimhan, B, Carlton, V, Zheng, J, Moorhead, M, Krampf, M R, Jones, C D, Waqar, A N, Faham, M, Zehnder, J L, Miklos, D B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740398/
https://www.ncbi.nlm.nih.gov/pubmed/23419792
http://dx.doi.org/10.1038/leu.2013.52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740398/
https://www.ncbi.nlm.nih.gov/pubmed/23419792
http://dx.doi.org/10.1038/leu.2013.52

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