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Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues

Aurachins are myxobacterial 3-farnesyl-4(1H)-quinolone derived compounds initially described as respiratory chain inhibitors, more specifically as inhibitors of various cytochrome complexes. They are also known as potent antibiotic compounds. We describe herein the first synthesis of aurachin D thro...

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Detalles Bibliográficos
Autores principales: Li, Xu-Wen, Herrmann, Jennifer, Zang, Yi, Grellier, Philippe, Prado, Soizic, Müller, Rolf, Nay, Bastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740496/
https://www.ncbi.nlm.nih.gov/pubmed/23946854
http://dx.doi.org/10.3762/bjoc.9.176