Activated Human T Cells Express Alternative mRNA Transcripts Encoding a Secreted Form of RANKL

Receptor activator of nuclear factor-kappaB -ligand (RANKL), encoded by the gene TNFSF11, is required for osteoclastogenesis, and its expression is upregulated in pathologic bone loss. Transcript variants of TNFSF11 mRNA have been described that encode a membrane-bound and a putative secreted form o...

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Detalles Bibliográficos
Autores principales: Walsh, NC, Alexander, KA, Manning, CA, Karmakar, S, Wang, JF, Weyand, CM, Pettit, AR, Gravallese, EM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740552/
https://www.ncbi.nlm.nih.gov/pubmed/23698708
http://dx.doi.org/10.1038/gene.2013.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740552/
https://www.ncbi.nlm.nih.gov/pubmed/23698708
http://dx.doi.org/10.1038/gene.2013.29

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