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Identification of ROCK1 kinase as a critical regulator of Beclin1 mediated autophagy during metabolic stress
The Ser/Thr Rho kinase 1 (ROCK1) is known to play major roles in a wide range of cellular activities, including those involved in tumor metastasis and apoptosis. Here we identify an indispensable function of ROCK1 in metabolic stress-induced autophagy. Applying a proteomics approach, we characterize...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740589/ https://www.ncbi.nlm.nih.gov/pubmed/23877263 http://dx.doi.org/10.1038/ncomms3189 |