Bioinspired total synthesis of katsumadain A by organocatalytic enantioselective 1,4-conjugate addition

Katsumadain A, a naturally occurring influenza virus neuraminidase (NA) inhibitor, was synthesized by using a bioinspired, organocatalytic enantioselective 1,4-conjugate addition of styryl-2-pyranone with cinnamaldehyde, followed by a tandem Horner–Wadsworth–Emmons/oxa Michael addition.

Detalles Bibliográficos
Autores principales: Wang, Yongguang, Bao, Ruiyang, Huang, Shengdian, Tang, Yefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740603/
https://www.ncbi.nlm.nih.gov/pubmed/23946860
http://dx.doi.org/10.3762/bjoc.9.182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740603/
https://www.ncbi.nlm.nih.gov/pubmed/23946860
http://dx.doi.org/10.3762/bjoc.9.182

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