A construction of 4,4-spirocyclic γ-lactams by tandem radical cyclization with carbon monoxide

A straightforward synthesis of 4,4-spirocyclic indol γ-lactams by tandem radical cyclization of iodoaryl allyl azides with CO was achieved. The reaction of iodoaryl allyl azides, TTMSS and AIBN under CO pressure (80 atm) in THF at 80 °C gave the desired 4,4-spirocyclic indoline, benzofuran, and oxin...

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Detalles Bibliográficos
Autores principales: Ueda, Mitsuhiro, Uenoyama, Yoshitaka, Terasoma, Nozomi, Doi, Shoko, Kobayashi, Shoji, Ryu, Ilhyong, Murphy, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740707/
https://www.ncbi.nlm.nih.gov/pubmed/23946829
http://dx.doi.org/10.3762/bjoc.9.151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740707/
https://www.ncbi.nlm.nih.gov/pubmed/23946829
http://dx.doi.org/10.3762/bjoc.9.151

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