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A reductive coupling strategy towards ripostatin A

Synthetic studies on the antibiotic natural product ripostatin A have been carried out with the aim to construct the C9−C10 bond by a nickel(0)-catalyzed coupling reaction of an enyne and an epoxide, followed by rearrangement of the resulting dienylcyclopropane intermediate to afford the skipped 1,4...

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Detalles Bibliográficos
Autores principales: Schleicher, Kristin D, Jamison, Timothy F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740708/
https://www.ncbi.nlm.nih.gov/pubmed/23946853
http://dx.doi.org/10.3762/bjoc.9.175