Genome-wide methylation profiling demonstrates hypermethylation in maternal leukocyte DNA in preeclamptic compared to normotensive pregnancies

OBJECTIVE: To compare genome-wide methylation profiles in maternal leukocyte DNA between normotensive and preeclamptic pregnant women at delivery. METHODS: Age, body mass index matched case-control comparison of methylation at 27,578 cytosine—guanine sites in 14,495 genes in maternal leukocyte DNA i...

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Detalles Bibliográficos
Autores principales: White, Wendy M., Brost, Brian, Sun, Zhifu, Rose, Carl, Craici, Iasmina, Wagner, Steven J., Turner, Stephen T., Garovic, Vesna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare USA, Inc. 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741019/
https://www.ncbi.nlm.nih.gov/pubmed/23782156
http://dx.doi.org/10.3109/10641955.2013.796970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741019/
https://www.ncbi.nlm.nih.gov/pubmed/23782156
http://dx.doi.org/10.3109/10641955.2013.796970

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