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Genome-wide methylation profiling demonstrates hypermethylation in maternal leukocyte DNA in preeclamptic compared to normotensive pregnancies
OBJECTIVE: To compare genome-wide methylation profiles in maternal leukocyte DNA between normotensive and preeclamptic pregnant women at delivery. METHODS: Age, body mass index matched case-control comparison of methylation at 27,578 cytosine—guanine sites in 14,495 genes in maternal leukocyte DNA i...
Autores principales: | White, Wendy M., Brost, Brian, Sun, Zhifu, Rose, Carl, Craici, Iasmina, Wagner, Steven J., Turner, Stephen T., Garovic, Vesna D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare USA, Inc.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741019/ https://www.ncbi.nlm.nih.gov/pubmed/23782156 http://dx.doi.org/10.3109/10641955.2013.796970 |
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