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Controlled progressive innate immune stimulation regimen prevents the induction of sickness behavior in the open field test

Peripheral immune activation by bacterial mimics or live replicating pathogens is well known to induce central nervous system activation. Sickness behavior alterations are often associated with inflammation-induced increases in peripheral proinflammatory cytokines (eg, interleukin [IL]-1β and IL-6)....

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Detalles Bibliográficos
Autores principales: Chen, Qun, Tarr, Andrew J, Liu, Xiaoyu, Wang, Yufen, Reed, Nathaniel S, DeMarsh, Cameron P, Sheridan, John F, Quan, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741056/
https://www.ncbi.nlm.nih.gov/pubmed/23950656
http://dx.doi.org/10.2147/JIR.S45111