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Controlled progressive innate immune stimulation regimen prevents the induction of sickness behavior in the open field test
Peripheral immune activation by bacterial mimics or live replicating pathogens is well known to induce central nervous system activation. Sickness behavior alterations are often associated with inflammation-induced increases in peripheral proinflammatory cytokines (eg, interleukin [IL]-1β and IL-6)....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741056/ https://www.ncbi.nlm.nih.gov/pubmed/23950656 http://dx.doi.org/10.2147/JIR.S45111 |