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Supplementation with Fish Oil and Genistein, Individually or in Combination, Protects Bone against the Adverse Effects of Methotrexate Chemotherapy in Rats

Cancer chemotherapy has been shown to induce long-term skeletal side effects such as osteoporosis and fractures; however, there are no preventative treatments. This study investigated the damaging effects of anti-metabolite methotrexate (MTX) subcutaneous injections (0.75 mg/kg BW) for five days and...

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Detalles Bibliográficos
Autores principales: Raghu Nadhanan, Rethi, Skinner, Jayne, Chung, Rosa, Su, Yu-Wen, Howe, Peter R., Xian, Cory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741109/
https://www.ncbi.nlm.nih.gov/pubmed/23951199
http://dx.doi.org/10.1371/journal.pone.0071592