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HLA-DRB1 Shared Epitope-Dependent DR-DQ Haplotypes Are Associated with Both Anti-CCP–Positive and –Negative Rheumatoid Arthritis in Chinese Han

The association between Human Leukocyte Antigen (HLA) class II and rheumatoid arthritis (RA) has been extensively studied, but few reported DR-DQ haplotype. Here we investigated the association of HLA-DRB1, DQA1, DQB1, and DR-DQ haplotypes with RA susceptibility and with anti-CCP antibodies in 281 R...

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Detalles Bibliográficos
Autores principales: Liu, Xu, Guo, Jianping, Jia, Yuan, Zhao, Yi, Liu, Xia, Cheng, Feng, Li, Xiaoxia, Zheng, Yi, Shi, Xuhua, Li, Haiyun, Huang, Cibo, Cheng, Yongjing, Lai, Bei, Huang, Yanhong, Wang, Tian, Ding, Bo, Li, ZhangGuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741114/
https://www.ncbi.nlm.nih.gov/pubmed/23951149
http://dx.doi.org/10.1371/journal.pone.0071373