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Functional Polymorphisms in FAS/FASL System Increase the Risk of Neuroblastoma in Chinese Population

The FAS and FASL system plays a substantial role in apoptosis and immune escape of cells. Three polymorphisms located in the promoter regions of FAS (-1377G/A and -670A/G) and FASL (-844T/C) have been shown to alter the transcriptional activity of the genes, respectively. This study was conducted to...

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Detalles Bibliográficos
Autores principales: Han, Wei, Zhou, Yuling, Zhong, Rong, Wu, Chen, Song, Ranran, Liu, Li, Zou, Li, Qiao, Yan, Zhai, Kan, Chang, Jiang, Huang, Liming, Lu, Xuzai, Lou, Jiao, Yu, Dianke, Tan, Wen, Zhang, Jinzhe, Wang, Huanmin, Miao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741122/
https://www.ncbi.nlm.nih.gov/pubmed/23951214
http://dx.doi.org/10.1371/journal.pone.0071656