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A Novel Naturally Occurring Tandem Promoter in Modified Vaccinia Virus Ankara Drives Very Early Gene Expression and Potent Immune Responses

Modified vaccinia virus Ankara (MVA) has been shown to be suitable for the generation of experimental vaccines against cancer and infectious diseases, eliciting strong humoral and cellular immune responses. In viral vectored vaccines, strong recombinant antigen expression and timing of expression in...

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Detalles Bibliográficos
Autores principales: Wennier, Sonia T., Brinkmann, Kay, Steinhäußer, Charlotte, Mayländer, Nicole, Mnich, Claudia, Wielert, Ursula, Dirmeier, Ulrike, Hausmann, Jürgen, Chaplin, Paul, Steigerwald, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741161/
https://www.ncbi.nlm.nih.gov/pubmed/23951355
http://dx.doi.org/10.1371/journal.pone.0073511