Structures of Streptococcus pneumoniae PiaA and Its Complex with Ferrichrome Reveal Insights into the Substrate Binding and Release of High Affinity Iron Transporters

Iron scarcity is one of the nutrition limitations that the Gram-positive infectious pathogens Streptococcus pneumoniae encounter in the human host. To guarantee sufficient iron supply, the ATP binding cassette (ABC) transporter Pia is employed to uptake iron chelated by hydroxamate siderophore, via...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Wang, Li, Qiong, Jiang, Yong-Liang, Zhou, Cong-Zhao, Chen, Yuxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741162/
https://www.ncbi.nlm.nih.gov/pubmed/23951167
http://dx.doi.org/10.1371/journal.pone.0071451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741162/
https://www.ncbi.nlm.nih.gov/pubmed/23951167
http://dx.doi.org/10.1371/journal.pone.0071451

Ejemplares similares