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Variability in Exposure of Epitope G40-R43 of Domain I in Commercial Anti-Beta2-Glycoprotein I IgG ELISAs
BACKGROUND: A major problem for diagnosing the antiphospholipid syndrome (APS) is the high variability between commercial anti-β(2)glycoprotein I (β(2)GPI) assays. Predominantly antibodies reactive against cryptic epitope Glycine40-Arginine43 (G40-R43) in domain I are associated with an increased ri...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741166/ https://www.ncbi.nlm.nih.gov/pubmed/23951154 http://dx.doi.org/10.1371/journal.pone.0071402 |