Variability in Exposure of Epitope G40-R43 of Domain I in Commercial Anti-Beta2-Glycoprotein I IgG ELISAs

BACKGROUND: A major problem for diagnosing the antiphospholipid syndrome (APS) is the high variability between commercial anti-β(2)glycoprotein I (β(2)GPI) assays. Predominantly antibodies reactive against cryptic epitope Glycine40-Arginine43 (G40-R43) in domain I are associated with an increased ri...

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Detalles Bibliográficos
Autores principales: Pelkmans, Leonie, Kelchtermans, Hilde, de Groot, Philip G., Zuily, Stephane, Regnault, Veronique, Wahl, Denis, Pengo, Vittorio, de Laat, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741166/
https://www.ncbi.nlm.nih.gov/pubmed/23951154
http://dx.doi.org/10.1371/journal.pone.0071402

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