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Enhanced Susceptibility to Spontaneous Seizures of Noda Epileptic Rats by Loss of Synaptic Zn(2+)

Zinc homeostasis in the brain is associated with the etiology and manifestation of epileptic seizures. Adult Noda epileptic rats (NER, >12-week-old) exhibit spontaneously generalized tonic-clonic convulsion about once a day. To pursue the involvement of synaptic Zn(2+) signal in susceptibility to...

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Detalles Bibliográficos
Autores principales: Takeda, Atsushi, Iida, Masashi, Ando, Masaki, Nakamura, Masatoshi, Tamano, Haruna, Oku, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741169/
https://www.ncbi.nlm.nih.gov/pubmed/23951148
http://dx.doi.org/10.1371/journal.pone.0071372