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Induction of a Feed Forward Pro-Apoptotic Mechanistic Loop by Nitric Oxide in a Human Breast Cancer Model

We have previously demonstrated that relatively high concentrations of NO [Nitric Oxide] as produced by activated macrophages induced apoptosis in the human breast cancer cell line, MDA-MB-468. More recently, we also demonstrated the importance of endogenous H(2)O(2) in the regulation of growth in h...

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Detalles Bibliográficos
Autores principales: Sen, Suvajit, Kawahara, Brian, Fukuto, Jon, Chaudhuri, Gautam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741195/
https://www.ncbi.nlm.nih.gov/pubmed/23950968
http://dx.doi.org/10.1371/journal.pone.0070593