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Induction of a Feed Forward Pro-Apoptotic Mechanistic Loop by Nitric Oxide in a Human Breast Cancer Model
We have previously demonstrated that relatively high concentrations of NO [Nitric Oxide] as produced by activated macrophages induced apoptosis in the human breast cancer cell line, MDA-MB-468. More recently, we also demonstrated the importance of endogenous H(2)O(2) in the regulation of growth in h...
Autores principales: | Sen, Suvajit, Kawahara, Brian, Fukuto, Jon, Chaudhuri, Gautam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741195/ https://www.ncbi.nlm.nih.gov/pubmed/23950968 http://dx.doi.org/10.1371/journal.pone.0070593 |
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