Alternative Splice Variants in TIM Barrel Proteins from Human Genome Correlate with the Structural and Evolutionary Modularity of this Versatile Protein Fold

After the surprisingly low number of genes identified in the human genome, alternative splicing emerged as a major mechanism to generate protein diversity in higher eukaryotes. However, it is still not known if its prevalence along the genome evolution has contributed to the overall functional prote...

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Detalles Bibliográficos
Autores principales: Ochoa-Leyva, Adrián, Montero-Morán, Gabriela, Saab-Rincón, Gloria, Brieba, Luis G., Soberón, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741200/
https://www.ncbi.nlm.nih.gov/pubmed/23950966
http://dx.doi.org/10.1371/journal.pone.0070582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741200/
https://www.ncbi.nlm.nih.gov/pubmed/23950966
http://dx.doi.org/10.1371/journal.pone.0070582

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