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The Tick-Derived Anticoagulant Madanin Is Processed by Thrombin and Factor Xa
The cysteine-less peptidic anticoagulants madanin-1 and madanin-2 from the bush tick Haemaphysalis longicornis are the founding members of the MEROPS inhibitor family I53. It has been previously suggested that madanins exert their functional activity by competing with physiological substrates for bi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741208/ https://www.ncbi.nlm.nih.gov/pubmed/23951260 http://dx.doi.org/10.1371/journal.pone.0071866 |