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The Tick-Derived Anticoagulant Madanin Is Processed by Thrombin and Factor Xa

The cysteine-less peptidic anticoagulants madanin-1 and madanin-2 from the bush tick Haemaphysalis longicornis are the founding members of the MEROPS inhibitor family I53. It has been previously suggested that madanins exert their functional activity by competing with physiological substrates for bi...

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Detalles Bibliográficos
Autores principales:	Figueiredo, Ana C., de Sanctis, Daniele, Pereira, Pedro José Barbosa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741208/ https://www.ncbi.nlm.nih.gov/pubmed/23951260 http://dx.doi.org/10.1371/journal.pone.0071866

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