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High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot

The potential importance of DNA methylation in the etiology of complex diseases has led to interest in the development of methylome-wide association studies (MWAS) aimed at interrogating all methylation sites in the human genome. When using blood as biomaterial for a MWAS the DNA is typically extrac...

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Detalles Bibliográficos
Autores principales: Aberg, Karolina A., Xie, Lin Y., Nerella, Srilaxmi, Copeland, William E., Costello, E. Jane, van den Oord, Edwin J.C.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741224/
https://www.ncbi.nlm.nih.gov/pubmed/23644822
http://dx.doi.org/10.4161/epi.24508