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Transcript Profiling Identifies Iqgap2(−/−) Mouse as a Model for Advanced Human Hepatocellular Carcinoma
It is broadly accepted that genetically engineered animal models do not always recapitulate human pathobiology. Therefore identifying best-fit mouse models of human cancers that truly reflect the corresponding human disease is of vital importance in elucidating molecular mechanisms of tumorigenesis...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741273/ https://www.ncbi.nlm.nih.gov/pubmed/23951254 http://dx.doi.org/10.1371/journal.pone.0071826 |