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EMT-Induced Stemness and Tumorigenicity Are Fueled by the EGFR/Ras Pathway
Recent studies have revealed that differentiated epithelial cells would acquire stem cell-like and tumorigenic properties following an Epithelial-Mesenchymal Transition (EMT). However, the signaling pathways that participate in this novel mechanism of tumorigenesis have not been fully characterized....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741305/ https://www.ncbi.nlm.nih.gov/pubmed/23950932 http://dx.doi.org/10.1371/journal.pone.0070427 |