Cargando…
EMT-Induced Stemness and Tumorigenicity Are Fueled by the EGFR/Ras Pathway
Recent studies have revealed that differentiated epithelial cells would acquire stem cell-like and tumorigenic properties following an Epithelial-Mesenchymal Transition (EMT). However, the signaling pathways that participate in this novel mechanism of tumorigenesis have not been fully characterized....
Autores principales: | Voon, Dominic Chih-Cheng, Wang, Huajing, Koo, Jason Kin Wai, Chai, Juin Hsien, Hor, Yit Teng, Tan, Tuan Zea, Chu, Yeh-Shiu, Mori, Seiichi, Ito, Yoshiaki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741305/ https://www.ncbi.nlm.nih.gov/pubmed/23950932 http://dx.doi.org/10.1371/journal.pone.0070427 |
Ejemplares similares
-
A Role for RUNX3 in Inflammation-Induced Expression of IL23A in Gastric Epithelial Cells
por: Hor, Yit Teng, et al.
Publicado: (2014) -
HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR
por: Ingthorsson, S, et al.
Publicado: (2016) -
Tumorigenicity of RTK/RAS in urothelium
por: Wu, Xue-Ru, et al.
Publicado: (2015) -
Metabolomic and Mitochondrial Fingerprinting of the Epithelial-to-Mesenchymal Transition (EMT) in Non-Tumorigenic and Tumorigenic Human Breast Cells
por: Cuyàs, Elisabet, et al.
Publicado: (2022) -
The EMT spectrum and therapeutic opportunities
por: Voon, Dominic C., et al.
Publicado: (2017)