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EMT-Induced Stemness and Tumorigenicity Are Fueled by the EGFR/Ras Pathway

Recent studies have revealed that differentiated epithelial cells would acquire stem cell-like and tumorigenic properties following an Epithelial-Mesenchymal Transition (EMT). However, the signaling pathways that participate in this novel mechanism of tumorigenesis have not been fully characterized....

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Detalles Bibliográficos
Autores principales: Voon, Dominic Chih-Cheng, Wang, Huajing, Koo, Jason Kin Wai, Chai, Juin Hsien, Hor, Yit Teng, Tan, Tuan Zea, Chu, Yeh-Shiu, Mori, Seiichi, Ito, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741305/
https://www.ncbi.nlm.nih.gov/pubmed/23950932
http://dx.doi.org/10.1371/journal.pone.0070427

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