Resistance Mutation R292K Is Induced in Influenza A(H6N2) Virus by Exposure of Infected Mallards to Low Levels of Oseltamivir

Resistance to neuraminidase inhibitors (NAIs) is problematic as these drugs constitute the major treatment option for severe influenza. Extensive use of the NAI oseltamivir (Tamiflu®) results in up to 865 ng/L of its active metabolite oseltamivir carboxylate (OC) in river water. There one of the nat...

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Detalles Bibliográficos
Autores principales: Gillman, Anna, Muradrasoli, Shaman, Söderström, Hanna, Nordh, Johan, Bröjer, Caroline, Lindberg, Richard H., Latorre-Margalef, Neus, Waldenström, Jonas, Olsen, Björn, Järhult, Josef D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741332/
https://www.ncbi.nlm.nih.gov/pubmed/23951116
http://dx.doi.org/10.1371/journal.pone.0071230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741332/
https://www.ncbi.nlm.nih.gov/pubmed/23951116
http://dx.doi.org/10.1371/journal.pone.0071230

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