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Efficient, Long Term Production of Monocyte-Derived Macrophages from Human Pluripotent Stem Cells under Partly-Defined and Fully-Defined Conditions

Human macrophages are specialised hosts for HIV-1, dengue virus, Leishmania and Mycobacterium tuberculosis. Yet macrophage research is hampered by lack of appropriate cell models for modelling infection by these human pathogens, because available myeloid cell lines are, by definition, not terminally...

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Detalles Bibliográficos
Autores principales: van Wilgenburg, Bonnie, Browne, Cathy, Vowles, Jane, Cowley, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741356/
https://www.ncbi.nlm.nih.gov/pubmed/23951090
http://dx.doi.org/10.1371/journal.pone.0071098