CCN Family Member 2/Connective Tissue Growth Factor (CCN2/CTGF) Has Anti-Aging Effects That Protect Articular Cartilage from Age-Related Degenerative Changes

To examine the role of connective tissue growth factor CCN2/CTGF (CCN2) in the maintenance of the articular cartilaginous phenotype, we analyzed knee joints from aging transgenic mice (TG) overexpressing CCN2 driven by the Col2a1 promoter. Knee joints from 3-, 14-, 40-, and 60-day-old and 5-, 12-, 1...

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Detalles Bibliográficos
Autores principales: Itoh, Shinsuke, Hattori, Takako, Tomita, Nao, Aoyama, Eriko, Yutani, Yasutaka, Yamashiro, Takashi, Takigawa, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741357/
https://www.ncbi.nlm.nih.gov/pubmed/23951098
http://dx.doi.org/10.1371/journal.pone.0071156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741357/
https://www.ncbi.nlm.nih.gov/pubmed/23951098
http://dx.doi.org/10.1371/journal.pone.0071156

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