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Enamel Matrix Derivative Inhibits Adipocyte Differentiation of 3T3-L1 Cells via Activation of TGF-βRI Kinase Activity

Enamel matrix derivative (EMD), an extract of fetal porcine enamel, and TGF-β can both suppress adipogenic differentiation. However, there have been no studies that functionally link the role of EMD and TGF-β in vitro. Herein, we examined whether TGF-β signaling contributes to EMD-induced suppressio...

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Detalles Bibliográficos
Autores principales: Gruber, Reinhard, Bosshardt, Dieter D., Miron, Richard J., Gemperli, Anja C., Buser, Daniel, Sculean, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741362/
https://www.ncbi.nlm.nih.gov/pubmed/23951076
http://dx.doi.org/10.1371/journal.pone.0071046