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Enamel Matrix Derivative Inhibits Adipocyte Differentiation of 3T3-L1 Cells via Activation of TGF-βRI Kinase Activity
Enamel matrix derivative (EMD), an extract of fetal porcine enamel, and TGF-β can both suppress adipogenic differentiation. However, there have been no studies that functionally link the role of EMD and TGF-β in vitro. Herein, we examined whether TGF-β signaling contributes to EMD-induced suppressio...
Autores principales: | Gruber, Reinhard, Bosshardt, Dieter D., Miron, Richard J., Gemperli, Anja C., Buser, Daniel, Sculean, Anton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741362/ https://www.ncbi.nlm.nih.gov/pubmed/23951076 http://dx.doi.org/10.1371/journal.pone.0071046 |
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