Targeting Rac1 Signaling Inhibits Streptococcal M1 Protein-Induced CXC Chemokine Formation, Neutrophil Infiltration and Lung Injury

Infections with Streptococcus pyogenes exhibit a wide spectrum of infections ranging from mild pharyngitis to severe Streptococcal toxic shock syndrome (STSS). The M1 serotype of Streptococcus pyogenes is most commonly associated with STSS. In the present study, we hypothesized that Rac1 signaling m...

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Detalles Bibliográficos
Autores principales: Zhang, Songen, Rahman, Milladur, Zhang, Su, Song, Lei, Herwald, Heiko, Thorlacius, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741375/
https://www.ncbi.nlm.nih.gov/pubmed/23951087
http://dx.doi.org/10.1371/journal.pone.0071080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741375/
https://www.ncbi.nlm.nih.gov/pubmed/23951087
http://dx.doi.org/10.1371/journal.pone.0071080

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