High Glucose Induces Connective Tissue Growth Factor Expression and Extracellular Matrix Accumulation in Rat Aorta Vascular Smooth Muscle Cells Via Extracellular Signal-Regulated Kinase 1/2

Connective tissue growth factor (CTGF) is a potent pro-fibrotic factor, which is implicated in fibrosis through extracellular matrix (ECM) induction in diabetic cardiovascular complications. It is an important downstream mediator in the fibrotic action of transforming growth factor β (TGFβ) and is p...

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Detalles Bibliográficos
Autores principales: Ha, Yu Mi, Lee, Dong Hyup, Kim, Mina, Kang, Young Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741487/
https://www.ncbi.nlm.nih.gov/pubmed/23946690
http://dx.doi.org/10.4196/kjpp.2013.17.4.307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741487/
https://www.ncbi.nlm.nih.gov/pubmed/23946690
http://dx.doi.org/10.4196/kjpp.2013.17.4.307

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