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Endonuclease V cleaves at inosines in RNA

Endonuclease V orthologues are highly conserved proteins found in all kingdoms of life. While the prokaryotic enzymes are DNA repair proteins for removal of deaminated adenosine (inosine) from the genome, no clear role for the eukaryotic counterparts has hitherto been described. Here we report that...

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Detalles Bibliográficos
Autores principales: Sebastian Vik, Erik, Sameen Nawaz, Meh, Strøm Andersen, Pernille, Fladeby, Cathrine, Bjørås, Magnar, Dalhus, Bjørn, Alseth, Ingrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741635/
https://www.ncbi.nlm.nih.gov/pubmed/23912683
http://dx.doi.org/10.1038/ncomms3271