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Computational Elucidation of Structural Basis for Ligand Binding with Leishmania donovani Adenosine Kinase
Enzyme adenosine kinase is responsible for phosphorylation of adenosine to AMP and is crucial for parasites which are purine auxotrophs. The present study describes development of robust homology model of Leishmania donovani adenosine kinase to forecast interaction phenomenon with inhibitory molecul...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741900/ https://www.ncbi.nlm.nih.gov/pubmed/23984386 http://dx.doi.org/10.1155/2013/609289 |