Cargando…

Computational Elucidation of Structural Basis for Ligand Binding with Leishmania donovani Adenosine Kinase

Enzyme adenosine kinase is responsible for phosphorylation of adenosine to AMP and is crucial for parasites which are purine auxotrophs. The present study describes development of robust homology model of Leishmania donovani adenosine kinase to forecast interaction phenomenon with inhibitory molecul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kar, Rajiv K., Ansari, Md. Yousuf, Suryadevara, Priyanka, Sahoo, Bikash R., Sahoo, Ganesh C., Dikhit, Manas R., Das, Pradeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741900/ https://www.ncbi.nlm.nih.gov/pubmed/23984386 http://dx.doi.org/10.1155/2013/609289

Ejemplares similares

Activity of a novel sulfonamide compound 2-nitro-N-(pyridin-2-ylmethyl)benzenesulfonamide against Leishmania donovani
por: Dikhit, Manas R, et al.
Publicado: (2016)

LeishMicrosatDB: open source database of repeat sequences detected in six fully sequenced Leishmania genomes
por: Dikhit, Manas R., et al.
Publicado: (2014)

The potential HLA Class I-restricted epitopes derived from LeIF and TSA of Leishmania donovani evoke anti-leishmania CD8+ T lymphocyte response
por: Dikhit, Manas Ranjan, et al.
Publicado: (2018)

Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut
por: Verma, Sudha, et al.
Publicado: (2017)

Elucidation of Novel Structural Scaffold in Rohu TLR2 and Its Binding Site Analysis with Peptidoglycan, Lipoteichoic Acid and Zymosan Ligands, and Downstream MyD88 Adaptor Protein
por: Sahoo, Bikash Ranjan, et al.
Publicado: (2013)

Identification of Potential MHC Class-II-Restricted Epitopes Derived from Leishmania donovani Antigens by Reverse Vaccinology and Evaluation of Their CD4+ T-Cell Responsiveness against Visceral Leishmaniasis
por: Dikhit, Manas Ranjan, et al.
Publicado: (2017)

A comparative protein function analysis databaseof different Leishmania strains
por: Dikhit, Manas Ranjan, et al.
Publicado: (2011)

Retraction Note: Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut
por: Verma, Sudha, et al.
Publicado: (2023)

Leishmania donovani Secretory Mevalonate Kinase Regulates Host Immune Response and Facilitates Phagocytosis
por: Bamra, Tanvir, et al.
Publicado: (2021)

Functional assignment to JEV proteins using SVM
por: Sahoo, Ganesh Chandra, et al.
Publicado: (2008)

Comparative domain modeling of human EGF-like module EMR2 and study of interaction of the fourth domain of EGF with chondroitin 4-sulphate()
por: Rani, Mukta, et al.
Publicado: (2011)

Differential Regulation of miRNA Profiles of Human Cells Experimentally Infected by Leishmania donovani Isolated From Indian Visceral Leishmaniasis and Post-Kala-Azar Dermal Leishmaniasis
por: Kumar, Ashish, et al.
Publicado: (2020)

CHPVDB ‐ a sequence annotation database for Chandipura Virus
por: Dikhit, Manas Ranjan, et al.
Publicado: (2009)

Elucidating the possible mechanism of action of some pathogen box compounds against Leishmania donovani
por: Amlabu, Wandayi Emmanuel, et al.
Publicado: (2020)

Universal minicircle sequence binding protein of Leishmania donovani regulates pathogenicity by controlling expression of cytochrome-b
por: Singh, Ruby, et al.
Publicado: (2016)

Corrigendum to “Role of remote sensing, geographic bioinformatics system and bioinformatics in kala-azar epidemiology” [originally published as J Biomed Res 2011, 25(6):373-384; doi:10.1016/S1674-8301(11)60050-X]
por: Bhunia, Gouri Sankar, et al.
Publicado: (2012)

Role of remote sensing, geographical information system (GIS) and bioinformatics in kala-azar epidemiology
por: Bhunia, Gouri Sankar, et al.
Publicado: (2011)

LEISHMANIA DONOVANI IN THE PERIPHERAL BLOOD
por: Young, Charles W., et al.
Publicado: (1923)

Retraction Note to: Universal minicircle sequence binding protein of Leishmania donovani regulates pathogenicity by controlling expression of cytochrome-b
por: Singh, Ruby, et al.
Publicado: (2022)

Interaction between Nbp35 and Cfd1 Proteins of Cytosolic Fe-S Cluster Assembly Reveals a Stable Complex Formation in Entamoeba histolytica
por: Anwar, Shadab, et al.
Publicado: (2014)

On Transient Infections with Leishmania Donovani in Man and Animals
por: Knowles, R., et al.
Publicado: (1924)

Proteomic analysis of the secretome of Leishmania donovani
por: Silverman, J Maxwell, et al.
Publicado: (2008)

Surface antigens of Leishmania donovani promastigotes
Publicado: (1983)

Vaccine Development Against Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2012)

Leishmania donovani bodies in bone marrow
por: Ali, Natasha, et al.
Publicado: (2014)

Cancrum Oris in a Monkey Infected with Leishmania Donovani
por: Smith, R. O. A.
Publicado: (1933)

Cytokines and splenic remodelling during Leishmania donovani infection
por: Montes de Oca, Marcela, et al.
Publicado: (2020)

The identification of kala-azar and the discovery of Leishmania donovani.
por: Gibson, M E
Publicado: (1983)

Leishmania donovani and Cutaneous Leishmaniasis, Sri Lanka
por: Siriwardana, H. V. Yamuna D., et al.
Publicado: (2007)

Leishmania donovani Develops Resistance to Drug Combinations
por: García-Hernández, Raquel, et al.
Publicado: (2012)

Hemophagocytosis in Experimental Visceral Leishmaniasis by Leishmania donovani
por: Morimoto, Ayako, et al.
Publicado: (2016)

Global genome diversity of the Leishmania donovani complex
por: Franssen, Susanne U, et al.
Publicado: (2020)

Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host
por: Verma, Sudha, et al.
Publicado: (2018)

Visceral Leishmaniasis Caused by Leishmania donovani Zymodeme MON-37, Western Ghats, India
por: Saini, Prasanta, et al.
Publicado: (2020)

Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient
por: Prasad, N., et al.
Publicado: (2011)

Central Asian Rodents as Model Animals for Leishmania major and Leishmania donovani Research
por: Vojtkova, Barbora, et al.
Publicado: (2020)

Bone marrow aspirate showing Leishmania donovani in polymorphs
por: Chandra, Harish, et al.
Publicado: (2013)

Seroepidemiology and molecular diversity of Leishmania donovani complex in Georgia
por: Babuadze, Giorgi, et al.
Publicado: (2016)

Fitness of Leishmania donovani Parasites Resistant to Drug Combinations
por: García-Hernández, Raquel, et al.
Publicado: (2015)

A Silver Method of Staining Leishmania Donovani in the Tissues
por: Basu, Charu Chandra
Publicado: (1927)

Cannot write session to /tmp/vufind_sessions/sess_ea2a9qjmlkss6dsdherht0b87k