The role of the N-terminal tail for the oligomerization, folding and stability of human frataxin()

The N-terminal stretch of human frataxin (hFXN) intermediate (residues 42–80) is not conserved throughout evolution and, under defined experimental conditions, behaves as a random-coil. Overexpression of hFXN56–210 in Escherichia coli yields a multimer, whereas the mature form of hFXN (hFXN81–210) i...

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Detalles Bibliográficos
Autores principales: Faraj, Santiago E., Venturutti, Leandro, Roman, Ernesto A., Marino-Buslje, Cristina B., Mignone, Astor, Tosatto, Silvio C.E., Delfino, José M., Santos, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741918/
https://www.ncbi.nlm.nih.gov/pubmed/23951553
http://dx.doi.org/10.1016/j.fob.2013.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741918/
https://www.ncbi.nlm.nih.gov/pubmed/23951553
http://dx.doi.org/10.1016/j.fob.2013.07.004

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