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Bisphenol A Modifies the Regulation Exerted by Testosterone on 5α-Reductase Isozymes in Ventral Prostate of Adult Rats

The development, growth, and function of the prostate gland depend on androgen stimulation. The primary androgen in prostate is 5α-dihydrotestosterone (DHT) which is synthesized from circulating testosterone (T) through the action of 5α-reductase (5α-R). Although 5α-R occurs as five isozymes, only 5...

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Detalles Bibliográficos
Autores principales: Sánchez, Pilar, Castro, Beatriz, Torres, Jesús M., Olmo, Asunción, del Moral, Raimundo G., Ortega, Esperanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741927/
https://www.ncbi.nlm.nih.gov/pubmed/23984391
http://dx.doi.org/10.1155/2013/629235