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All-trans retinoic acid modulates mitogen-activated protein kinase pathway activation in human scleral fibroblasts through retinoic acid receptor beta

PURPOSE: All-trans retinoic acid (ATRA) is known to inhibit the proliferation of human scleral fibroblasts (HSFs) and to modulate the scleral intercellular matrix composition, and may therefore serve as a mediator for controlling eye growth. Cell proliferation is regulated by the mitogen-activated p...

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Detalles Bibliográficos
Autores principales: Huo, Lijun, Cui, Dongmei, Yang, Xiao, Gao, Zhenya, Trier, Klaus, Zeng, Junwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742120/
https://www.ncbi.nlm.nih.gov/pubmed/23946634