ROS and ERK1/2-mediated caspase-9 activation increases XAF1 expression in dexamethasone-induced apoptosis of EBV-transformed B cells

Dexamethasone (Dex) inhibits the growth of diverse types of cancer cells and is utilized clinically for the therapy of hematological malignancies. In this study, we investigated the molecular mechanisms of Dex action in the apoptosis of Epstein-Barr virus (EBV)-transformed B cells. We showed that De...

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Detalles Bibliográficos
Autores principales: PARK, GA BIN, CHOI, YUNOCK, KIM, YEONG SEOK, LEE, HYUN-KYUNG, KIM, DAEJIN, HUR, DAE YOUNG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742161/
https://www.ncbi.nlm.nih.gov/pubmed/23685456
http://dx.doi.org/10.3892/ijo.2013.1949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742161/
https://www.ncbi.nlm.nih.gov/pubmed/23685456
http://dx.doi.org/10.3892/ijo.2013.1949

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