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Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells

Soybean isoflavones have been used as a potential preventive agent in anticancer research for many years. Genistein is one of the most active flavonoids in soybeans. Accumulating evidence suggests that genistein alters a variety of biological processes in estrogen-related malignancies, such as breas...

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Detalles Bibliográficos
Autores principales: ZHANG, ZHIYU, WANG, CHONG-ZHI, DU, GUANG-JIAN, QI, LIAN-WEN, CALWAY, TYLER, HE, TONG-CHUAN, DU, WEI, YUAN, CHUN-SU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742162/
https://www.ncbi.nlm.nih.gov/pubmed/23686257
http://dx.doi.org/10.3892/ijo.2013.1946