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Reinvestigation of the Oxidative Folding Pathways of Hen Egg White Lysozyme: Switching of the Major Pathways by Temperature Control

It has been well established that in the oxidative folding of hen egg white lysozyme (HEL), which has four SS linkages in the native state (N), three des intermediates, i.e., des[76–94], des[64–80], and des [6–127], are populated at 20 °C and N is dominantly formed by the oxidation of des[64–80] and...

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Detalles Bibliográficos
Autores principales: Arai, Kenta, Shibagaki, Wataru, Shinozaki, Reina, Iwaoka, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742182/
https://www.ncbi.nlm.nih.gov/pubmed/23803654
http://dx.doi.org/10.3390/ijms140713194